The novel Ampha X30 opens a new era of cell analysis: simultaneous measurement of cell count and cell viability, and in addition crucial information about the status of the cells, like metabolic activity.

UNIQUE

With the Ampha X30 all cell types can be analyzed with one instrument, using chips with different channel diameters. The cells are not harmed by the measurement and due to the absence of dyes and markers, the cells can be recovered and reused, e.g., for sorting or tissue culture.

• All cell types like bacteria, human and animal, algae, yeast, somatic cells

• Reuse of cells for sorting, tissue culture

• One instrument, four chips,all cells

ENTERPRIS

One chip lasts for 1000 measurements and no markers or dyes are required which reduces the operational cost. In addition, no incubation time is needed which shortens the whole measurement to few minutes – from sample preparation until the result.

• No staining, no molecular markers, no incubation needed

• Low operation cost

• Fast and simple sample preparation and measurement: results immediately available

FLEXIBLE

The instrument is highly flexible and can be used for online analysis via a bypass of the reaction solution. The sample can be pumped from the reactor directly through the microfluidic chip and back into the reactor. The sophisticated software thereby facilitates measurement and data analysis and integrated wizards promote a simple workflow.

• Online analysis via bypass approach

• Sophisticated software for measurement and data analysis

• Maintenance wizards for daily simple usage

Case study: Beer Fermentation

Yeast viability can be affected by various factors, such as temperature, pH, and the presence of contaminants. The fermentation of beer was monitored over a course of seven days. In parallel, cell viability and cell concentration were determined. The shift of the viable cell populations every day (Figure C; shift of the populations day 1 red to day 2 green and day 3 blue to the left) indicates a change in metabolic activity: from a low ethanol concentration and aerobic conditions at the beginning the cells change into an anaerobic activity producing large amounts of ethanol after three days (Opitz et al., 2019).